Why have domestic rabbits been used in scientific research?

Domestic rabbits are frequently used in scientific research primarily because they are easily raised in captivity. Their use as laboratory animals is a significant component of biomedical research, where they serve as models for studying human diseases, developing treatments, and ensuring product safety.12

Specifically, rabbits are often utilized in eye and skin irritation tests, particularly within the cosmetics and chemical safety industries.2

The use of animals in such research is a subject of significant ethical debate, centering on the moral responsibility to protect sentient beings from pain and suffering versus the potential benefits of scientific and medical advancement. Modern research practices are increasingly guided by the "three Rs" principle—replacement, reduction, and refinement—which aims to minimize animal use and ensure that any necessary research is conducted with strict oversight to prioritize animal welfare and minimize distress.2