Which animals are most closely related to sloths?

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Sloths are most closely related to anteaters, with which they share the order Pilosa. Together, sloths and anteaters are grouped with armadillos to form the magnorder Xenarthra.123

Members of the Xenarthra lineage are characterized by unique joints in their lower backbone, known as "xenarthrous" vertebrae, which strengthen the hips and lower back. Additionally, these animals share physiological traits such as low metabolic rates and cooler body temperatures compared to other mammals of similar size. While modern xenarthrans are restricted to the Western Hemisphere, their evolutionary history includes various extinct relatives, such as the ground sloths and glyptodonts.32