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What substance helps form an arthropod’s exoskeleton?

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The primary substance that forms an arthropod's exoskeleton is chitin, a high-molecular-weight polysaccharide.1

In arthropods, the epidermis secretes a tough cuticle composed of chitin fibers embedded in a matrix of protein. This structure is often reinforced through sclerotization, a process that stabilizes protein chains to create a natural plastic known as sclerotin. Additionally, the exoskeleton features an outer, water-resistant layer of wax that helps prevent dehydration in terrestrial environments. In some species, such as crustaceans, the cuticle may also be hardened by the incorporation of mineral substances like calcite or aragonite.123